News From Transplant Week of January 6, 2002 / Vol. 3 No. 1

 

Tests Proposed of New Therapy for Chronic Transplant Rejection

 

AtheroGenics, Inc. announced that it had asked the U.S. Food and Drug Administration for permission to initiate clinical trials of AGI-1096, a novel, oral drug for the prevention of organ transplant
rejection.

"Because of the unique properties of this compound, we are encouraged by the prospect of bringing forward a new therapy for patients at risk for chronic transplant rejection," said Dr. Russell M. Medford, president of AtheroGenics.

Medford said AGI-1096 is an anti-inflammatory agent that both diminishes the transplant response to inflammation, a contributing factor in chronic rejection, and directly protects the blood vessels to the transplanted organ, potentially providing a unique and complementary therapy to existing immunosuppressants.

Other sources: AtheroGenics