University of Pittsburgh
doctors have given a woman who received a transplanted kidney
donated by her brother some of his blood stem cells in an experimental
attempt to reduce her need for anti-rejection medications.
Sharon Long, 54, of
Bradford, got a 20-minute transfusion of blood stem cells three
days after receiving the transplanted kidney from her 47-year-old
brother.
While doctors have
previously transplanted bone marrow into kidney recipients in
an effort to keep the kidney from being rejected by the patient's
immune system, this is the first reported instance of transplant
doctors using a technique called peripheral blood stem cell transplantation.
This procedure previously
has been used in cancer treatment to restore stem cells that have
been destroyed by high doses of chemotherapy and/or radiation
therapy.
Instead of obtaining
stem cells from bone marrow, the stem cells are obtained from
circulating blood after the donor takes medication to increase
their numbers.
As part of the experiment,
Long is not taking steroids -- a mainstay of anti-rejection treatment
for most transplant recipients.