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Three transplant patients
contracted a dangerous parasitic disease from their new organs,
and one of the three died of the disease, according to the U.S.
Centers for Disease Control and Prevention.
The transplants
are linked to Emory University, though whether the organs were
retrieved there or the transplants took place there has not been
disclosed. Emory representatives would say only that they were
aware of the cases.
A 37-year-old
who received a kidney-pancreas transplant died of Chagas disease
in October; a 32-year-old who received a liver transplant died
of transplant complications in July; and a 69-year-old who received
the other kidney was treated for four months and is recovering.
Names and hometowns were not disclosed.
The infected
organs all came from the cadaver of a Central American immigrant
who was apparently infected with T. cruzi, a parasite which causes
Chagas disease, the CDC said.
The disease,
previously confined to Latin America, can cause heart irregularities.
Ten percent to 30 percent of people infected with the parasite
develop full-blown Chagas disease.
More than
16 million people are reported to be infected by the parasite
in Central and South America, and CDC officials estimated as many
as 100,000 Latin American immigrants in the United States may
carry the parasite. Since the disease can lie dormant in the body
for many years, neither the Central American donor nor the donor's
family may have known of the infection.
The women
are the first known cases of Chagas being transmitted by transplant
in the United States, said Dr. Barbara Herwaldt of the CDC. The
CDC said it was consulting with transplant organizations nationwide
to decide whether to start screening for T. cruzi.
"It's
a complex issue," said Herwaldt. "Which donors would
be screened? What test would be used? Right now even blood donors
aren't screened for this infection."
"We screen
for a large number of potentially transmissible illnesses -- for
HIV, hepatitis and a whole host of other things," said Dr.
Christian P. Larsen, director of the Emory Transplant Center.
"The problem is that there are a whole host of diseases around
the world that are potentially transmissible, and it is exceedingly
difficult given the time constraints of organ donation to be able
to screen for every conceivable illness."
Other
sources: CDC, Atlanta Journal and Constitution
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