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Patients
who are HIV-positive and need an organ transplant should have
equal access to organs from cadaver donors, three medical ethicists
argue in the current issue of the New England Journal of Medicine.
Dr. Arthur
Caplan and Scott D. Halpern of the University of Pennsylvania
and Dr. Peter Ubel of the Veterans Affairs Ann Arbor Healthcare
System in Michigan argue that drugs have turned HIV into a chronic
infection that isn't necessarily a death sentence, and that many
people infected with the virus now live for years.
They further
contend that there is no evidence to suggest that the immunosuppressive
drugs taken by transplant recipients increase an HIV patient's
susceptibility to infection.
The researchers
note that most transplant programs offer organs to people with
other conditions that can affect how long they survive such as
hepatitis C and diabetes.
"On ethical
grounds alone, there is no justification for providing organs
to these groups of patients but not to patients infected with
HIV," the authors write.
With more
than 80,000 Americans on growing transplant waiting lists, many
transplant surgeons have been opposed to using scarce organs for
HIV patients. But in the past couple of years, this view has begun
to change.
A spokesperson
for the United Network on Organ Sharing (UNOS), which coordinates
distribution of organs, said its figures show that in 2001, 26
HIV-positive patients received donor kidneys and 22 received liver
transplants. The actual total would be somewhat higher because
California and a number of other states prohibit disclosure of
a patient's HIV status.
Other
sources: New England Journal of Medicine, UNOS
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