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While cardiovascular
risk factors for liver transplant recipients are higher in the
first years after their surgery, the risk factors are no greater
than those of the general population by five years after transplantation,
according to Spanish researchers.
The researchers,
reporting in the journal Transplant International on their study
of 116 stable liver transplant recipients who had survived for
at least five years, speculated that the reduction over time in
hypertension, diabetes, hypercholesterolemia and hypertriglyceridemia
might be linked to the tapering off of steroids.
The researchers
also reported that patients taking cyclosporine as their primary
anti-rejection medication had a higher prevalence of hypertension,
hypercholesterolemia and hyperhomocysteinemia than those taking
Prograf.
"We conclude
that the prevalence of cardiovascular risk factors in liver transplant
patients after 5 years or more is lower that found in the first
years after the transplantation, and no different from that found
within the Spanish population," the researchers reported.
Other
sources: Transplant International
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