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The potential
pool of brain-dead organ donors under the age of 70 in the United
States is smaller than previously believed, and would not provide
enough organs to for waiting transplant patients even if every
one of them became a donor, according to researchers.
In a report
in the New England Journal of Medicine, the researchers said a
review of hospital medical records of deaths occurring from 1997
through 1999 led them to conclude that the annual number of brain-dead
potential organ donors is between 10,500 and 13,800 out of the
two million Americans who die each year.
Some previous
studies had suggested that the number might be more than twice
that high.
"It's
a game of small numbers, and every opportunity needs to be maximized,"
said Ellen Sheehy, who led the study for the Association of Organ
Procurement Organizations.
In their study,
the researchers identified 18,524 potential donors who had suffered
brain death from trauma such as a car crash, massive brain bleeding,
or another cause.
"The
overall consent rate (the number of families agreeing to donate
divided by the number of families asked to donate) for 1997 through
1999 was 54 percent, and the overall conversion rate (the number
of actual donors divided by the number of potential donors) was
42 percent," the researchers reported.
They said
hospitals with 150 or more beds were more likely to be a potential
source of organ donors, with 19 percent of hospitals accounting
for 80 percent of all potential donors.
"Since
potential and actual donors are highly concentrated in larger
hospitals, resources invested to improve the process of obtaining
consent in larger hospitals should maximize the rate of organ
recovery," the researchers concluded.
Other
Sources: New England Journal of Medicine
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